placebo-controlled trials in osteoporosis: ethical challenges
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Placebo-controlled trials in osteoporosis--proceeding with caution.
This article presents one viewpoint on the issues surrounding placebo-controlled trials in osteoporosis. The other Sounding Board article in this issue presents an opposing view. At NEJM.org, in a related interactive feature, the authors of each article give their Point of View about the other article. At NEJM.org, readers can participate in forming community opinion by choosing one of the view...
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Much controversy exists regarding the ethics of placebo-controlled trials in which an experimental therapy will compete with an already established treatment (or treatments). In such cases, argue critics, patients in the control arm of the study should receive an accepted therapy rather than a placebo. By using an active and effective drug, the control patients would not be placed at risk for d...
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اخلاق و تاریخ پزشکیجلد ۵، شماره ۲، صفحات ۸۰-۸۳
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